Title :
Platforms for controlled release of antibacterial agents facilitated by plasma polymerization
Author :
Vasilev, Krasimir ; Simovic, Spomenka ; Losic, Dusan ; Griesser, Hans J. ; Griesser, Stefani ; Anselme, Karine ; Ploux, Lydie
Author_Institution :
Mawson Inst., Univ. of South Australia, Adelaide, SA, Australia
fDate :
Aug. 31 2010-Sept. 4 2010
Abstract :
Bacterial infections present an enormous problem causing human suffering and cost burdens to the healthcare systems worldwide. Herein we present several versatile strategies for controlled release of antibacterial agents which include silver ions as well as traditional antibiotics. At the heart of these release platforms is a thin film deposited by plasma polymerization. The use of plasma polymerization makes these strategies applicable to the surface of many types of medical devices since the technique for deposition of a polymer film from plasma in practically substrate independent.
Keywords :
antibacterial activity; biomedical equipment; drug delivery systems; drugs; plasma materials processing; polymer films; polymerisation; silver; vapour deposition; Ag; antibiotics; bacterial infections; controlled antibacterial agent release platforms; medical devices; plasma deposited thin film; plasma polymerization; polymer thin film deposition; silver ions; Antibiotics; Ions; Microorganisms; Plasmas; Polymer films; Silver; Anti-Bacterial Agents; Delayed-Action Preparations; Diffusion; Drug Compounding; Gases; Hot Temperature; Materials Testing; Membranes, Artificial; Polymers; Silver;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location :
Buenos Aires
Print_ISBN :
978-1-4244-4123-5
DOI :
10.1109/IEMBS.2010.5626566