Title :
Observing folding and catalysis of a single RNA enzyme molecule
Author :
Zhuang, X. ; Bartley, L. ; Babcock, H. ; Russell, R. ; Ha, T. ; Herschlag, D. ; Chu, S.
Author_Institution :
Dept. of Phys., Stanford Univ., CA, USA
Abstract :
Summary form only given.RNA enzyme molecules form complex and specific structures that are able to perform a variety of structure-related functions. Yet the mechanism by which an RNA molecule folds into a unique structure is largely unknown. In this paper, we demonstrate that single molecules fluorescence microscopy is a power tool to study RNA folding.
Keywords :
biological techniques; fluorescence; macromolecules; optical microscopy; organic compounds; RNA folding; RNA molecule folding; single RNA enzyme molecule; single molecule fluorescence microscopy; structure-related functions; Biochemistry; Energy exchange; Kinetic theory; RNA;
Conference_Titel :
Lasers and Electro-Optics, 2000. (CLEO 2000). Conference on
Conference_Location :
San Francisco, CA, USA
Print_ISBN :
1-55752-634-6
DOI :
10.1109/CLEO.2000.907428
