Spontaneous patterning obtained by evaporation of Human Elastin-like Polypeptide solutions

Author

Bandiera, Antonella ; Urbani, Ranieri ; Sist, Paola

Author_Institution

Dept., Univ. of Trieste, Trieste, Italy

fYear

2010

fDate

Aug. 31 2010-Sept. 4 2010

Firstpage

819

Lastpage

822

Abstract

The potential of producing patterned, bioactive coatings with Human Elastin-Like Polypeptides (HELPs) has been investigated. The physicochemical features of these compounds have evidenced some differences between the two recombinantly expressed products. By a device-free, simple route and avoiding the use of chemically unfriendly compounds, micropatterned surfaces with the ability to control cell behavior could be obtained. Thus, HELPs represent a very promising class of macromolecule for future applications in surface engineering.

Keywords

biochemistry; biomedical materials; cellular biophysics; coatings; evaporation; macromolecules; molecular biophysics; proteins; bioactive coatings; cell behavior; evaporation; human elastin-like polypeptides; macromolecule; micropatterned surfaces; physicochemical features; spontaneous patterning; Coatings; Geometry; Humans; Polymers; Surface morphology; Surface treatment; Binding Sites; Coated Materials, Biocompatible; Desiccation; Elastin; Humans; Materials Testing; Peptides; Protein Binding; Solutions;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE

Conference_Location

Buenos Aires

ISSN

1557-170X

Print_ISBN

978-1-4244-4123-5

Type

conf

DOI

10.1109/IEMBS.2010.5626761

Filename

5626761