Novel Magnetic Materials for Diagnostic and Separation Applications

Paramagnetic particles have emerged as important tools for cell sorting, protein separation, and single molecule measurements. The particles used in these applications must meet the following requirements: uniform in size, highly paramagnetic, stable in physiological salt buffer, functionizable, and 100-1000 nanometers in size. We have developed several new templated nanofabrication techniques for preparing paramagnetic particles with that meet these criteria. We will describe these new materials and their application for the detection of model pathogens.