Title :
A method for reducing fouling at the sensor-sample interface
Author :
Gregory, C.M. ; Hatfield, J V ; Higgins, S. ; Vadgama, P.J.
Author_Institution :
Dept. of Electr. Eng. & Electron., Univ. of Manchester Inst. of Sci. & Technol., UK
Abstract :
A method of reducing fouling/biofouling on the active surface of sensors in unclean environments is presented. The effect exploited in this system depends on differences in the diffusion coefficients of the analytes (or microsolutes) and foulants (or cellular material). Details of the fabrication and testing are given. Results of experiments with a micromachined flow cell are presented and contrasted with those of a computational fluid dynamics model. Modelling shows effective repulsion of foulants and predicts a signal strength consistent with experimental results
Keywords :
biological techniques; cellular biophysics; channel flow; computational fluid dynamics; diffusion; electrochemical sensors; active surface; cellular material; computational fluid dynamics; diffusion coefficients; effective repulsion; fabrication; foulants; fouling/biofouling; micromachined flow cell; sensor-sample interface; signal strength; testing; unclean environments; Amperometric sensors; Biochemistry; Biological materials; Biosensors; Blood; Electrodes; Fabrication; Hospitals; Sensor phenomena and characterization; Sensor systems;
Conference_Titel :
Instrumentation and Measurement Technology Conference, 1999. IMTC/99. Proceedings of the 16th IEEE
Conference_Location :
Venice
Print_ISBN :
0-7803-5276-9
DOI :
10.1109/IMTC.1999.776777
