Surface acoustic wave resonators as novel tools for multiparametric blood analysis

Author

Guhr, G. ; Brünig, R. ; Schmidt, H. ; Weihnacht, M. ; Gehrisch, S. ; Siegert, G.

Author_Institution

IFW Dresden, Dresden, Germany

fYear

2010

fDate

Aug. 31 2010-Sept. 4 2010

Firstpage

3499

Lastpage

3502

Abstract

In this paper a new tool to assess viscoelastic and dielectric properties of human fluids is presented. Shear horizontal polarized surface acoustic waves (SH-SAW) are used to detect the viscoelastic properties of coagulating blood and blood plasma samples. One-port SAW resonators, with fundamental modes of 85, 170 und 340 MHz were developed. Additionally, their electrode structures can be used simultaneously to detect the dielectric behavior of the whole system by impedance spectroscopy while the frequency ranges from kHz to MHz. The combination of both methods offers the detection of clinical relevant blood parameters like the blood coagulation time and the hematocrit value within one measurement.

Keywords

biomedical electrodes; biomedical measurement; blood; coagulation; dielectric properties; haemodynamics; surface acoustic wave resonators; viscoelasticity; blood coagulation time; blood plasma samples; dielectric properties; electrode structures; hematocrit value; human fluids; impedance spectroscopy; multiparametric blood analysis; one-port SAW resonators; shear horizontal polarized surface acoustic waves; surface acoustic wave resonators; viscoelastic properties; Coagulation; Impedance; Plasmas; Resonant frequency; Surface acoustic waves; Surface impedance; Acoustics; Biosensing Techniques; Blood Chemical Analysis; Complex Mixtures; Equipment Design; Equipment Failure Analysis; Micro-Electrical-Mechanical Systems;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE

Conference_Location

Buenos Aires

ISSN

1557-170X

Print_ISBN

978-1-4244-4123-5

Type

conf

DOI

10.1109/IEMBS.2010.5627792

Filename

5627792