DocumentCode
2954158
Title
3-D flow characterization and shear stress in a stenosed carotid artery bifurcation model using stereoscopic PIV technique
Author
Kefayati, Sarah ; Poepping, Tamie L.
Author_Institution
Dept. of Phys. & Astron., Univ. of Western Ontario, London, ON, Canada
fYear
2010
fDate
Aug. 31 2010-Sept. 4 2010
Firstpage
3386
Lastpage
3389
Abstract
The carotid artery bifurcation is a common site of atherosclerosis which is a major leading cause of ischemic stroke. The impact of stenosis in the atherosclerotic carotid artery is to disturb the flow pattern and produce regions with high shear rate, turbulence, and recirculation, which are key hemodynamic factors associated with plaque rupture, clot formation, and embolism. In order to characterize the disturbed flow in the stenosed carotid artery, stereoscopic PIV measurements were performed in a transparent model with 50% stenosis under pulsatile flow conditions. Simulated ECG gating of the flowrate waveform provides external triggering required for volumetric reconstruction of the complex flow patterns. Based on the three-component velocity data in the lumen region, volumetric shear-stress patterns were derived.
Keywords
bifurcation; biomedical optical imaging; blood vessels; electrocardiography; flow visualisation; haemodynamics; image reconstruction; medical image processing; pulsatile flow; shear flow; turbulence; 3-D flow characterization; atherosclerosis; clot formation; disturbed flow; embolism; external triggering; flowrate waveform; hemodynamic factors; high shear rate; ischemic stroke; lumen region; plaque rupture; pulsatile flow; recirculation; shear stress; simulated ECG gating; stenosed carotid artery bifurcation model; stereoscopic PIV technique; three-component velocity data; turbulence; volumetric reconstruction; Bifurcation; Carotid arteries; Fluids; Hemodynamics; Phantoms; Solid modeling; Stress; Animals; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Carotid Stenosis; Computer Simulation; Humans; Models, Anatomic; Models, Cardiovascular; Rheology; Shear Strength;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE
Conference_Location
Buenos Aires
ISSN
1557-170X
Print_ISBN
978-1-4244-4123-5
Type
conf
DOI
10.1109/IEMBS.2010.5627933
Filename
5627933
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