Title :
The spatial structure of the cardio active peptides
Author :
Akhmedov, N.A. ; Abbasli, R.M. ; Ismailova, L.I.
Author_Institution :
Inst. for Phys. Problems, Baku State Univ., Baku, Azerbaijan
Abstract :
One of the basic problems for molecular physics is investigating of the spatial organization of the peptide molecules and their structure-functional organization. This work is devoted to study the spatial organization, conformational possibilities of the class of cardio active peptides for the first time. The calculations were carried out by the method of theoretical conformational analysis. Basing the calculation results the simulated analogues of each peptide molecule are constructed, the conformational mobility of the amino acid side chains are investigated and the amino acids with specific interplays with different receptors are founded.
Keywords :
cardiology; molecular biophysics; molecular configurations; amino acid side chain conformational mobility; cardio active peptide spatial structure; molecular physics; peptide conformations; peptide spatial organisation; peptide structure-function organisation; theoretical conformational analysis; Amino acids; Astronomy; Cardiology; Field-flow fractionation; Peptides; Physics; Physiology; Radio frequency; analogue; conformation; molecule; peptide; structure;
Conference_Titel :
Application of Information and Communication Technologies, 2009. AICT 2009. International Conference on
Conference_Location :
Baku
Print_ISBN :
978-1-4244-4739-8
Electronic_ISBN :
978-1-4244-4740-4
DOI :
10.1109/ICAICT.2009.5372609