Thrombolysis in the eyes of the continuous wavelet transform

Author

Toledo, E. ; Gurevitz, O. ; Hod, H. ; Eldar, M. ; Akselrod, S.

Author_Institution

Tel Aviv Univ., Israel

fYear

2002

fDate

22-25 Sept. 2002

Firstpage

657

Lastpage

660

Abstract

Acute myocardial infarction (MI) is known to elicit autonomic responses, depending on its location: inferior-wall MI (Inf-MI) promotes vagal activation, and anterior-wall MI (Ant-MI) promotes sympathetic activation. Reperfusion is thus expected to induce an opposite shift in autonomic balance. We studied the patterns of heart rate variability (HRV), which reflect the autonomic response to reperfusion by applying a continuous wavelet transform (CWT). ECG traces, 3 h long, were obtained from 9 Ant-MI and 8 Inf-MI patients during acute MI. Marked alterations in HRV occurred in all reperfusion events. A shift in balance towards sympathetic predominance was found in all Inf-MI patients, and in 3 Ant-MI patients, while a shift towards vagal predominance was found in 6 Ant-MI patients (p<0.001). The CWT thus enables to study cardiac control during non-steady-state conditions, as exhibited during thrombolysis.

Keywords

electrocardiography; medical signal processing; wavelet transforms; acute myocardial infarction; autonomic balance; autonomic responses; continuous wavelet transform; heart rate variability; nonsteady-state conditions; sympathetic activation; thrombolysis; vagal activation; vagal predominance; Continuous wavelet transforms; Equations; Eyes; Frequency; Heart rate; Heart rate variability; Ischemic pain; Myocardium; Spectral analysis; Wavelet transforms;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 2002

ISSN

0276-6547

Print_ISBN

0-7803-7735-4

Type

conf

DOI

10.1109/CIC.2002.1166858

Filename

1166858