Title :
Noninvasive multi-modality nonlinear imaging of heart development using transgenic zebrafish lines tagged with Hc-red fluorescence proteins
Author :
Tsai, Tsung-Han ; Chen, Szu-Yu ; Lin, Cheng-Yung ; Tsai, Huai-Jen ; Sun, Chi-Kuang
Author_Institution :
Graduate Inst. of Electro-Opt. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
We generated zebrafish lines with two-photon red fluorescence expressed in the heart excited by 1230 nm light. With high penetration and high viability, heart development dynamics deep inside live embryos is noninvasively revealed in vivo.
Keywords :
biomedical optical imaging; cardiology; fluorescence; molecular biophysics; proteins; two-photon processes; 1230 nm; Hc-red fluorescence proteins; heart development; live embryos; noninvasive multi-modality nonlinear imaging; transgenic zebrafish lines; two-photon red fluorescence; Biomedical optical imaging; Embryo; Fluorescence; Heart; Nonlinear optics; Optical harmonic generation; Optical microscopy; Optical scattering; Protein engineering; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN :
1-55752-795-4
DOI :
10.1109/CLEO.2005.202428
