DocumentCode
2990225
Title
A Hydrogel-based Microvalve for Insulin Delivery Application
Author
Tehranirokh, Masoomeh ; Bais, Badariah ; Majlis, Burhanuddin Yeop
Author_Institution
Univ. Kebangsaan Malaysia, Bangi
fYear
2006
fDate
Oct. 29 2006-Dec. 1 2006
Firstpage
167
Lastpage
171
Abstract
A hydrogel-actuated microvalve that responds to changes in the concentration of glucose in an external liquid environment is described. The microvalve consists of a thin hydrogel, sandwiched between a stiff porous membrane and a flexible silicon rubber diaphragm. Swelling of the hydrogel forces the membrane to deflect therefore boss causes the valve to be opened. Simulations have been done by FEM analysis and the results show enough deflection to open the valve and let the fluid flow through the microchannel to obtain 130 microliter/min for output flow.
Keywords
bioMEMS; drug delivery systems; finite element analysis; microactuators; microchannel flow; microvalves; swelling; FEM analysis; flexible silicon rubber diaphragm; glucose; hydrogel-actuated microvalve; insulin delivery; microchannel flow; stiff porous membrane; swelling; Analytical models; Biomembranes; Fluid flow; Insulin; Microchannel; Microvalves; Rubber; Silicon; Sugar; Valves;
fLanguage
English
Publisher
ieee
Conference_Titel
Semiconductor Electronics, 2006. ICSE '06. IEEE International Conference on
Conference_Location
Kuala Lumpur
Print_ISBN
0-7803-9730-4
Electronic_ISBN
0-7803-9731-2
Type
conf
DOI
10.1109/SMELEC.2006.381041
Filename
4266591
Link To Document