• DocumentCode
    2995581
  • Title

    Branching DNA machines based on transitions of hairpin structures

  • Author

    Kubota, Minoru ; Ohtake, Kazumasa ; Komiya, Kazuki ; Sakamoto, Kensaku ; Hagiya, Masami

  • Author_Institution
    Dept. of Comput. Sci., Tokyo Univ., Japan
  • Volume
    4
  • fYear
    2003
  • fDate
    8-12 Dec. 2003
  • Firstpage
    2542
  • Abstract
    We constructed a DNA machine, the state branches of which depend on input DNA oligomers. The machine is a single DNA oligomer consisting of two hairpin structures connected by a single-stranded section. The input DNA oligomers can invade a hairpin´s stem via branch migration, opening the hairpin. The branching state is represented by which of the hairpins is opened. This paper describes the design of the DNA machine, an analysis of secondary structure transitions, and experimental results.
  • Keywords
    DNA; biology computing; biotechnology; evolutionary computation; DNA machine; DNA oligomers; hairpin structures transitions; Biochemistry; Biophysics; Biotechnology; Computer science; DNA computing; Information science; Molecular computing; Nanotechnology; Switches; Tiles;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2003. CEC '03. The 2003 Congress on
  • Print_ISBN
    0-7803-7804-0
  • Type

    conf

  • DOI
    10.1109/CEC.2003.1299408
  • Filename
    1299408