Title :
Branching DNA machines based on transitions of hairpin structures
Author :
Kubota, Minoru ; Ohtake, Kazumasa ; Komiya, Kazuki ; Sakamoto, Kensaku ; Hagiya, Masami
Author_Institution :
Dept. of Comput. Sci., Tokyo Univ., Japan
Abstract :
We constructed a DNA machine, the state branches of which depend on input DNA oligomers. The machine is a single DNA oligomer consisting of two hairpin structures connected by a single-stranded section. The input DNA oligomers can invade a hairpin´s stem via branch migration, opening the hairpin. The branching state is represented by which of the hairpins is opened. This paper describes the design of the DNA machine, an analysis of secondary structure transitions, and experimental results.
Keywords :
DNA; biology computing; biotechnology; evolutionary computation; DNA machine; DNA oligomers; hairpin structures transitions; Biochemistry; Biophysics; Biotechnology; Computer science; DNA computing; Information science; Molecular computing; Nanotechnology; Switches; Tiles;
Conference_Titel :
Evolutionary Computation, 2003. CEC '03. The 2003 Congress on
Print_ISBN :
0-7803-7804-0
DOI :
10.1109/CEC.2003.1299408
