DocumentCode
3001617
Title
Clinical trial factors in a pain transition state model
Author
Katzper, Meyer
Author_Institution
Center for Drug Evaluation & Res., Food & Drug Adm., Rockville, MD, USA
fYear
2005
fDate
4-7 Dec. 2005
Abstract
This paper presents a pain state transition model which accounts for constraints used in clinical trials. The pain transition state model is an approach for summarizing, presenting and modeling pain state transitions in a population. Data used are from the ibuprofen arm of a number of clinical trials measuring dental extraction pain. The data determine the state transition coefficients of the model. The pain process in the presence of an analgesic is thus fully characterized.
Keywords
dentistry; medical computing; clinical trial factors; dental extraction pain; ibuprofen arm; pain transition state model; Biological system modeling; Clinical trials; Data mining; Dentistry; Drugs; Pain; Teeth; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Simulation Conference, 2005 Proceedings of the Winter
Print_ISBN
0-7803-9519-0
Type
conf
DOI
10.1109/WSC.2005.1574511
Filename
1574511
Link To Document