Multimodal Optical Tissue Imaging

Author

Tang, Shuo ; Zhou, Yifeng ; Lai, Tom ; Ju, Myeong Jin

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of British Columbia, Vancouver, BC, Canada

fYear

2012

fDate

21-23 May 2012

Firstpage

1

Lastpage

3

Abstract

This paper presents tissue imaging with a multimodal multiphoton microscopy (MPM) and optical coherence tomography (OCT) system. The multimodal system can acquire multiple contrasts including two-photon excited fluorescence, second harmonic generation, and scattering. The system can also acquire tissue level imaging with OCT and cellular level imaging with MPM. The MPM/OCT imaging is demonstrated on onion skin and cornea samples. The multimodal MPM/OCT provides a multi-contrast and multi-field-of-view imaging system which has potential applications in cancer detection and diagnosis.

Keywords

biomedical optical imaging; cancer; fluorescence spectroscopy; light scattering; multiphoton spectroscopy; optical harmonic generation; optical microscopy; optical tomography; MPM-OCT imaging; cancer detection; cancer diagnosis; cellular level imaging; cornea sample; light scattering; multicontrast multifield of view imaging system; multimodal multiphoton microscopy; multimodal optical tissue imaging; onion skin sample; optical coherence tomography; second harmonic generation; tissue level imaging; two photon excited fluorescence; Biomedical optical imaging; Coherence; Image resolution; Nonlinear optics; Optical harmonic generation; Optical imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

Photonics and Optoelectronics (SOPO), 2012 Symposium on

Conference_Location

Shanghai

ISSN

2156-8464

Print_ISBN

978-1-4577-0909-8

Type

conf

DOI

10.1109/SOPO.2012.6271131

Filename

6271131