Title :
Label-free Optical Biosensor Built with Two-Dimensional Silicon Photonic Crystal Microcavity
Author :
Lee, Mindy ; Fauchet, Philippe M.
Author_Institution :
Univ. of Rochester, Rochester
Abstract :
We experimentally demonstrate a silicon-based photonic crystal microcavity biosensor. This device is capable of detecting ~1 femtogram of analyte. Its performance is tested with glutaraldehyde-BSA model for quantitative measurements and biotin-streptavidin recognition for selectivity demonstration.
Keywords :
biosensors; optical sensors; photonic crystals; silicon; 2D silicon photonic crystal microcavity; biotin-streptavidin recognition; glutaraldehyde-BSA model; label-free optical biosensor; mass 1 fg; quantitive measurements; selectivity property; Biomedical optical imaging; Biosensors; Microcavities; Optical interferometry; Optical refraction; Optical resonators; Optical sensors; Photonic crystals; Silicon; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2007. CLEO 2007. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-834-6
DOI :
10.1109/CLEO.2007.4452904
