Title :
An Integrated System for Multichannel Neuronal Recording with Spike / LFP Separation and Digital Output
Author :
Perelman, Yevgeny ; Ginosar, Ran
Author_Institution :
Dept. of Electr. Eng., Israel Inst. of Technol., Haifa
Abstract :
A mixed-signal front-end processor for multichannel neuronal recording is described. It receives twelve differential-input channels of implanted recording electrodes. A programmable cutoff HPF blocks DC and low frequency input drift. The signals are band-split at about 200 Hz to low frequency local field potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF. Amplifier offsets are compensated by calibration DACs. The SPK and LFP channels provide variable amplification rates of up to 5000 and 500, respectively. The analog signals are converted into digital form, and streamed out over a serial digital bus. A threshold filter supresses inactive portions of the signal and emits only spike segments. A prototype has been fabricated on a 0.35/mum CMOS process and tested successfully
Keywords :
bioelectric potentials; biomedical electrodes; filters; medical signal processing; neurophysiology; satellite computers; CMOS process; amplifier; differential-input channels; digital output; high-frequency spike data; integrated system; low frequency local field potential; mixed-signal front-end processor; multichannel neuronal recording; programmable cutoff HPF; spike/local field potential separation; threshold filter; CMOS process; Calibration; Communication system control; Cutoff frequency; Digital recording; Electrodes; Radio access networks; Registers; Sorting; Very large scale integration;
Conference_Titel :
Neural Engineering, 2005. Conference Proceedings. 2nd International IEEE EMBS Conference on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7803-8710-4
DOI :
10.1109/CNE.2005.1419637