Novel Material for Patterned Neural Networks

Author

Barrett, Eric W. ; Silva, Ricardo J. ; Wilson, Diane E. ; Natale, Donald ; Gaumond, Roger P. ; Allcock, Harry R.

Author_Institution

Dept. of Chem., Pennsylvania State Univ., University Park, PA

fYear

2005

fDate

16-19 March 2005

Firstpage

563

Lastpage

565

Abstract

Two polyphosphazenes were synthesized: poly[bis(trifluoroethoxy)phosphazene] (TFE) and poly[(methoxyethoxyethoxy)1.0(p-cresoxy)1.0 phosphazene] (PMPP). These materials were selected due to their properties in order to provide a conductive cell friendly substrate to couple cells to electrode plates (PMPP) and an isolative cell unfriendly polymer to coat the rest of the system (TFE). Materials properties were tested and analyzed using well known physicochemical methods and cell selectivity was tested using a human derived neuroblastoma cell line (SK-N-BE(2c)). Materials proved to behave as expected, opening the door for the use of polyphosphazenes in patterned neural network systems

Keywords

bioelectric phenomena; biomedical electrodes; biomedical materials; cellular biophysics; neural nets; polymers; cell selectivity; conductive cell friendly substrate; electrode plates; isolative cell unfriendly polymer; neuroblastoma cell line (SK-N-BE(2c); patterned neural network systems; patterned neural networks; physicochemical methods; poly[(methoxyethoxyethoxy)1.0(p-cresoxy)1.0 phosphazene]; poly[bis(trifluoroethoxy)phosphazene]; polyphosphazenes; Adhesives; Biological materials; Chemistry; Conducting materials; Electrodes; Material properties; Materials testing; Neural networks; Polymers; Substrates;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Engineering, 2005. Conference Proceedings. 2nd International IEEE EMBS Conference on

Conference_Location

Arlington, VA

Print_ISBN

0-7803-8710-4

Type

conf

DOI

10.1109/CNE.2005.1419685

Filename

1419685