Title :
A distributed architecture for a general cellular modeling and simulation framework
Author :
Schaff, James C.
Author_Institution :
Dept. of Physiol., Connecticut Univ. Health Center, Storrs, CT, USA
Abstract :
The Virtual Cell is a general framework for the spatial modeling and simulation of cellular physiology. Biochemical reaction models are topologically organized by their cellular location and are mapped to image-based cell geometry. The corresponding mathematical system is automatically generated and solved. A system architecture is described that allows the integration of heterogeneous processes and available resources while managing the overall system complexity
Keywords :
cellular biophysics; medical image processing; medical information systems; Virtual Cell; biochemical reaction models; cellular location; cellular modeling and simulation framework; distributed architecture; image-based cell geometry; mathematical system; spatial modeling; system complexity; Biochemistry; Biological system modeling; Biomembranes; Electron microscopy; Geometry; Kinetic theory; Mathematical model; Physiology; Solid modeling; Spatial resolution;
Conference_Titel :
Computer-Based Medical Systems, 1999. Proceedings. 12th IEEE Symposium on
Conference_Location :
Stamford, CT
Print_ISBN :
0-7695-0234-2
DOI :
10.1109/CBMS.1999.781294
