Dextrous stick coordination manipulation for 3D hydrogel assembly by dual-nanomanipulator

A novel dextrous stick coordination manipulation (DeSCom) system with dual-nanomanipulator was proposed for the assembly of three-dimensional (3D) structures. The coordination control between two dextrous sticks was realized based on the vision feedback and the manipulation resolution was around 30 nm. It was set up with hybrid motors to ensure the large operation range and operation precision. The dextrous stick was fabricated with glass pipette and the 2-dimensional (2D) unit was fabricated by UV illumination of the hydrogen named Poly (ethylene glycol) Diacrylate (PEGDA). The immobilization and assembly of 2D unit was achieved through the interaction of two sticks. The DeSCom system could realize the arbitrary 3D structure with the change of 2D unit shape through the different patterning with UV illumination. At last, the bottom-up integration of the 3D structure was performed based on the utilization of DeSCom strategies with image processing information. The preliminary assembly experiment was achieved.