Light microendoscopy with MEMS technology

Progress toward early diagnosis of cancer would have important clinical benefits in reducing cancer mortality; thus, there is an urgent need to improve cancer screening by providing in vivo real-time high-resolution diagnosis through optical imaging modalities. Microelectromechanical systems (MEMS) based optical endoscopes have been playing a key role in miniaturization of fiber-optical endoscopy for cancer diagnosis for over 30 years. In this paper, both review and technology outlook of MEMS based fiber-optical microendoscopy for real-time in vivo disease diagnosis will be provided.