• DocumentCode
    3019851
  • Title

    Brownian dynamics simulation of ion channels embedded in silicon membranes for sensor applications

  • Author

    Berti, C. ; Furini, S. ; Sangiorgi, E. ; Fiegna, C.

  • Author_Institution
    ARCES, Univ. of Bologna, Cesena, Italy
  • fYear
    2011
  • fDate
    14-16 March 2011
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    In this work we present a three-dimensional numerical simulation technique for the study of ion permeation through ion channels embedded in silicon membranes, that can be exploited for sensor applications. The results of this work clarify how the charges embedded in the protein forming the ion channel can influence ionic conductance through silicon membrane slabs, controlling the channel conductance and selectivity with respect to ionic species.
  • Keywords
    Brownian motion; biosensors; elemental semiconductors; lipid bilayers; numerical analysis; proteins; silicon; Brownian dynamics simulation; Si; channel conductance; ion channels; ion permeation; ionic conductance; protein; sensor applications; silicon membrane slabs; silicon membranes; three-dimensional numerical simulation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Ultimate Integration on Silicon (ULIS), 2011 12th International Conference on
  • Conference_Location
    Cork
  • Print_ISBN
    978-1-4577-0090-3
  • Electronic_ISBN
    978-1-4577-0089-7
  • Type

    conf

  • DOI
    10.1109/ULIS.2011.5757953
  • Filename
    5757953