Title :
Experimental study on Love-wave sensors with SiO2/LiTaO3 structures
Author :
Zhou, Feng-mei ; Li, Zhe ; Zhang, Tao ; Lin, Wei ; Fan, Li ; Gong, Xun ; Zhang, Shu-yi
Author_Institution :
Inst. of Acoust., Nanjing Univ., Nanjing
Abstract :
In this paper, a kind of Love wave sensors with SiO2/36degYX LiTaO3 structures for monitoring antibody-antigen immunoreactions in aqueous solutions in real time is presented. In this study, the devices with low insertion losses are achieved when the devices are in direct contact with the solutions. In the immunosensing measurements, a goat anti human-immunoglobulin G (HigG) is immobilized on the device surface as a receptor layer for detecting HigG in buffer solution. The results show that the structures have high sensitivity, which demonstrate that the sensors are very effective for biological and chemical sensing applications in liquid environments.
Keywords :
biochemistry; biosensors; chemical sensors; lithium compounds; molecular biophysics; proteins; silicon compounds; surface acoustic wave sensors; Love-wave sensor; SiO2-LiTaO3; antibody-antigen immunoreactions; aqueous solution; biological sensor; chemical sensor; human-immunoglobulin G; immunosensing measurement; insertion loss; Acoustic devices; Acoustic sensors; Biosensors; Chemical and biological sensors; Dielectric substrates; Frequency; Immune system; Insertion loss; Monitoring; Polymers; Love wave device; bio-chemical sensor; immunosensing measurement;
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0457
