A surface acoustic wave sensor for detection of cell adhesion

Author

Guhr, Glen ; Brünig, Raimund ; Jäger, Martin ; Poll, Rüdiger ; Schmidt, Hagen ; Weihnacht, Manfred

Author_Institution

Solid State & Mater. Res. Dresden, Leibniz Inst., Dresden

fYear

2008

fDate

2-5 Nov. 2008

Firstpage

1948

Lastpage

1950

Abstract

In this paper preliminary results for the detection of the cell adhesion process with shear-horizontal polarized surface acoustic wave devices (SH-SAW) are presented. The murine fibroblast cell line L929 was investigated. Therefore a special measurement setup was developed. It enables us to perform long term measurements at stable ambient conditions. Different amounts of cells where seeded. According to the number of cells different slopes of resonant frequency increase vs. time were found.

Keywords

adhesion; biosensors; cellular biophysics; surface acoustic wave sensors; cell adhesion process detection; cell-based biosensor; murine fibroblast cell line L929; resonant frequency; shear-horizontal polarized SAW devices; surface acoustic wave devices; surface acoustic wave sensor; Acoustic measurements; Acoustic sensors; Acoustic signal detection; Acoustic waves; Adhesives; Fibroblasts; Performance evaluation; Polarization; Surface acoustic wave devices; Surface acoustic waves; L929; cell adhesion; cell based biosensor; surface acoustic wave (SAW);

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 2008. IUS 2008. IEEE

Conference_Location

Beijing

Print_ISBN

978-1-4244-2428-3

Electronic_ISBN

978-1-4244-2480-1

Type

conf

DOI

10.1109/ULTSYM.2008.0480

Filename

4803520