Title :
Ultrasonic molecular imaging of primordial angiogenic vessels in the papilloma virus transgenic mouse with αvβ3-integrin targeted nanoparticles using Renyi entropy-based signal detection
Author :
Wallace, Kirk D. ; Marsh, Jon N. ; Thomas, Lewis J., III ; Neuman, Robert G. ; Arbeit, Jeffery M. ; Lanza, Gregory M. ; Wickline, Samuel A.
Author_Institution :
Sch. of Med., Washington Univ. in St. Louis, Saint Louis, MO
Abstract :
Previously we reported on an entropy-based signal receiver and demonstrated that, in certain settings, it was more sensitive to subtle changes in scattering architecture than conventional energy-based signal characterization. In this paper we present results demonstrating further improvements in sensitivity using a signal receiver based on the Renyi-entropy.
Keywords :
biomedical ultrasonics; entropy; medical signal detection; microorganisms; nanobiotechnology; nanoparticles; Renyi entropy-based signal detection; alphavbeta3-integrin targeted nanoparticles; papilloma virus transgenic mouse; primordial angiogenic vessels; ultrasonic molecular imaging; Biomedical imaging; Density functional theory; Energy measurement; Entropy; Hafnium; Mice; Molecular imaging; Nanoparticles; Radio frequency; Signal processing; HPV mouse; Renyi entropy; information-theoretic detector; molecular imaging; targeted nanoparticle;
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0090
