Title :
Development of diagnostic imaging system for regional lymph node micrometastasis with high-frequency ultrasound
Author :
Tomita, Noriko ; Horie, Sachiko ; Oosawa, Fuki ; Watanabe, Yukiko ; Chen, Rui ; Ohki, Kosuke ; Morikawa, Hirohide ; Fukumoto, Manabu ; Mori, Shiro ; Kodama, Tetsuya
Author_Institution :
Grad. Sch. of Biomed. Eng., Tohoku Univ., Sendai
Abstract :
It is important of diagnosing not only primary tumors but also metastases accurately. Recently, we have established murine lymph node metastasis model and developed a new method to reconstruct the two- and three-dimensional (2D/3D) vessel structures in the model by using nanobubbles (NBs) and high-frequency ultrasound imaging system. In the present study, we investigated the characteristics of 2D/3D vessel structures in the metastasis model, and compared to normal lymph node. This technique may be useful for early diagnosis of lymph node micrometastasis.
Keywords :
biomedical ultrasonics; blood vessels; image reconstruction; tumours; 2D vessel structures reconstruction; 3D vessel structures reconstruction; diagnostic imaging system; high frequency ultrasound; nanobubbles; regional lymph node micrometastasis; tumors; Axilla; Biomedical imaging; Cancer detection; Luminescence; Lymph nodes; Metastasis; Mice; Neoplasms; Shape; Ultrasonic imaging; angiogenesis; diagnosis; high-frequency ultrasound; nanobubble lymph node metastasis;
Conference_Titel :
Ultrasonics Symposium, 2008. IUS 2008. IEEE
Conference_Location :
Beijing
Print_ISBN :
978-1-4244-2428-3
Electronic_ISBN :
978-1-4244-2480-1
DOI :
10.1109/ULTSYM.2008.0423