DocumentCode
3038337
Title
A new neural network ensemble heuristic for a predictor of the aldose reductase inhibitory activity
Author
Parra-Hernandez, R. ; Laxdal, E.M. ; Dimopoulos, N.J. ; Alexiou, Polyxeni
Author_Institution
Dept. of Electr. & Comput., Victoria Univ., BC
fYear
2005
fDate
21-21 Dec. 2005
Firstpage
838
Lastpage
843
Abstract
In this paper, we present a mechanism to obtain a neural network-based model that predicts an enzyme inhibitory activity of a group of compounds. The mechanism selects the compounds, among a sparse set of, that should be used to obtain models of the inhibitory activity of interest. That is, the mechanism is aimed to the selection of a training set of compounds which will ensure that the training of a neural network-based model will result in a system capable of generalization
Keywords
enzymes; inhibitors; neural nets; aldose reductase inhibitory activity; enzyme inhibitory activity; neural network ensemble heuristic; Biochemistry; Biological system modeling; Cancer; Chemical compounds; Databases; Electronic mail; Inhibitors; Neural networks; Pharmaceuticals; Predictive models;
fLanguage
English
Publisher
ieee
Conference_Titel
Signal Processing and Information Technology, 2005. Proceedings of the Fifth IEEE International Symposium on
Conference_Location
Athens
Print_ISBN
0-7803-9313-9
Type
conf
DOI
10.1109/ISSPIT.2005.1577208
Filename
1577208
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