DocumentCode
3041885
Title
Feature Extraction of Colon Cancer´s Gene
Author
Liu, Guangya ; Duan, Bin
Author_Institution
Coll. of Electr. & Electron. Eng., Hubei Univ. of Technol., Wuhan, China
fYear
2011
fDate
14-17 Dec. 2011
Firstpage
287
Lastpage
290
Abstract
In this paper, the gene features associated with colon cancer were extracted from the given colon cancer gene expression data by reasonable statistical methods and other mathematical methods. Firstly, the majority(80%-90%), of unrelated genes of which the linear normalized distance was below 0.2 were removed using Bhattacharyya weighted distance, then the weight of the corresponding trait genes and the corresponding threshold value were derived using the linear kernel SVM training feature gene subset. We found the best combination of genes(2-60) and picked out the optimal combination of genes with the lowest error rate as the ultimate combination of genes(5-7). Finally, we tested the optimal combination of genes on the test set and the error rate was below 3%, indicating high precision.
Keywords
mathematical analysis; medical computing; statistical analysis; support vector machines; Bhattacharyya weighted distance; colon cancer gene; error rate; feature extraction; gene expression data; linear kernel SVM training feature gene subset; linear normalized distance; mathematical methods; statistical methods; test set; Cancer; Colon; Gene expression; Support vector machines; Testing; Training; Bhattacharyya weighted distance; FFSM; SVM;
fLanguage
English
Publisher
ieee
Conference_Titel
Intelligent Computation and Bio-Medical Instrumentation (ICBMI), 2011 International Conference on
Conference_Location
Wuhan, Hubei
Print_ISBN
978-1-4577-1152-7
Type
conf
DOI
10.1109/ICBMI.2011.12
Filename
6131765
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