A super-resolution CMOS image sensor for bio-microfluidic imaging

Author

Tongxi Wang ; Xiwei Huang ; Qixiang Jia ; Mei Yan ; Hao Yu ; Kiat Seng Yeo

Author_Institution

Sch. of Electr. & Electron. Eng., Nanyang Technol. Univ. (NTU), Singapore, Singapore

fYear

2012

fDate

28-30 Nov. 2012

Firstpage

388

Lastpage

391

Abstract

A super-resolution CMOS image sensor is introduced in this paper for bio-microfluidic imaging. Compared to the traditional scientific CCD or CMOS image sensor, our design achieves the balance between high-sensitivity and high-resolution from system design perspective with the use of single-frame super-resolution. Moreover, the column-parallel image sensor architecture with correlated-double-sampling is deployed for high-speed and low-noise readout. The chip is designed in standard 0.18μm CMOS mixed-signal process with area of 2.5mm×5.0mm, 128×128 pixel-array and speed of 1750 frames/s. The resolution is improved by 4X by on-chip super-resolution algorithm while large pixel (10μm×10μm) is employed in image sensor for high-sensitivity.

Keywords

CMOS image sensors; bioMEMS; biomedical equipment; image resolution; image sampling; integrated circuit layout; medical image processing; microfluidics; microsensors; mixed analogue-digital integrated circuits; readout electronics; CMOS mixed-signal process; biomicrofluidic imaging; column-parallel image sensor; correlated-double-sampling; high-speed readout; low-noise readout; on-chip super-resolution algorithm; super-resolution CMOS image sensor; Biomedical imaging; CMOS image sensors; Signal resolution; Spatial resolution; System-on-a-chip;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2012 IEEE

Conference_Location

Hsinchu

Print_ISBN

978-1-4673-2291-1

Electronic_ISBN

978-1-4673-2292-8

Type

conf

DOI

10.1109/BioCAS.2012.6418415

Filename

6418415