Title :
Rapid detection of E.Coli bacteria using potassium-sensitive FETs in CMOS
Author :
Nikkhoo, Nasim ; Gulak, P. Glenn ; Maxwell, Karen
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Toronto, Toronto, ON, Canada
Abstract :
An integrated bacteria detection chip is implemented in 0.18μm CMOS technology. The chip has been tested using phages as biological detecting elements along with CMOS ion-selective FETs to detect the presence of a specific strain of E.coli. The chip successfully identifies the presence of living bacterial strains sensitive to the T6 phage in less than 30 minutes. Potassium-sensitive ISFETS are implemented using CMOS ISFETs and a post-processed potassium-sensitive PVC-based membrane on the top layer.
Keywords :
CMOS integrated circuits; biomembranes; biosensors; cellular biophysics; ion sensitive field effect transistors; microorganisms; polymers; potassium; CMOS ISFET; CMOS ion-selective FET; CMOS technology; E.coli bacteria; E.coli strain; T6 phage; biological detecting elements; integrated bacteria detection chip; living bacterial strains; post-processed potassium-sensitive PVC-based membrane; potassium-sensitive FET; potassium-sensitive ISFET; rapid detection; size 0.18 mum; top layer; Biomembranes; CMOS integrated circuits; CMOS technology; Ions; Microorganisms; Transducers;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2012 IEEE
Conference_Location :
Hsinchu
Print_ISBN :
978-1-4673-2291-1
Electronic_ISBN :
978-1-4673-2292-8
DOI :
10.1109/BioCAS.2012.6418470
