Title :
Opto-μECoG array: Transparent μECoG electrode array and integrated LEDs for optogenetics
Author :
Ki Yong Kwon ; Sirowatka, Brenton ; Wen Li ; Weber, Andreas
Author_Institution :
ECE Dept., Michigan State Univ., East Lansing, MI, USA
Abstract :
In this work, we developed an integrated Opto-μECoG array, which allows multi-channel, bi-directional interaction with neurons. The Opto-μECoG array comprises a 6×5 distribution of epidural microelectrodes (~200 μm diameter) for electrical recording and embedded light emitting diodes (LEDs) for optical neural stimulation. Transparent electrodes were fabricated with indium tin oxide (ITO). Commercially available LED chips were self-assembled on a flexible polymer substrate as light sources. Parylene C served as the main structural and packaging material for flexibility and biocompatibility. Electrical and optical characteristics of the fabricated device were studied and in-vivo experiments were performed to investigate the efficacy of the device.
Keywords :
biomedical electrodes; electroencephalography; genetics; indium compounds; light emitting diodes; light sources; medical signal processing; microelectrodes; neurophysiology; optical neural nets; polymers; self-assembly; ITO; LED; LED chips; bidirectional interaction; biocompatibility; electrical characteristics; electrical recording; epidural microelectrodes; flexibility; flexible polymer substrate; in-vivo experiments; indium tin oxide; integrated LED; integrated opto-μECoG array; light emitting diodes; light sources; multichannel interaction; neurons; optical characteristics; optical neural stimulation; optogenetics; packaging material; parylene C; self-assembly; structural material; transparent μECoG electrode array; transparent electrodes; Arrays; Biomedical optical imaging; Electrodes; Indium tin oxide; Light emitting diodes; Optical device fabrication; Stimulated emission;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2012 IEEE
Conference_Location :
Hsinchu
Print_ISBN :
978-1-4673-2291-1
Electronic_ISBN :
978-1-4673-2292-8
DOI :
10.1109/BioCAS.2012.6418471
