Live demonstration: A portable closed-loop seizure controller in freely moving rats

A portable seizure controller that consists of a neural interface and an embedded platform as shown in Figure 1 was demonstrated. The neural interface has an EEG amplifier for data acquisition and a stimulator to provide responsive electrical stimulation. Several tasks are implemented on the embedded platform including analog-to-digital conversion of EEG signals, execution of seizure detection algorithm, generation of pulse trains to stimulator and wireless transmission of EEG data to the host for monitoring and recording. Table 1 summarizes the weight and dimension of the seizure controller. The demonstration contains two parts. First, the system will be presented on the demonstration site of Biocas 2012. The other one is live demonstration. The system will be mounted on a rat with absence seizures. The rat can freely move and the system including the seizure detector and the electrical stimulator will be turned on to demonstrate the effectiveness of the seizure controller.