Title :
Influence of SOD Mimics on Activities of Cultured Hepatoma Cell Line
Author :
Shumao, Ding ; Wang Liming ; Zhanru, Liao ; Hongfei, Li
Author_Institution :
Lab. of Environ. Sci. Coll. of Life Sci., Huazhong Normal Univ., Wuhan
Abstract :
Based on the free radical theory, considerable effort has been made in biochemistry to develop SOD mimics as therapeutic agents to eliminate excessive free radicals. Among widely used mimics, the SOD mimics (also named as the model of SOD, MSOD) have been indicated promising results with the possible future applications as a new antitumor medicine in clinic. The present study showed that this SOD mimic can inhibit the proliferation of human hepatoma SSMC-7721 cells and significantly affect cell cycles. These preliminary findings may pave the way for its wider application.
Keywords :
biochemistry; cellular biophysics; enzymes; free radicals; molecular biophysics; patient treatment; biochemistry; cell proliferation; cultured hepatoma cell line; free radical theory; human hepatoma SSMC-7721 cells; inhibition effect; superoxide dismutase mimics; Biochemistry; Biological materials; Bovine; Cancer; Cells (biology); Diseases; Drugs; Educational institutions; Humans; Organisms;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
DOI :
10.1109/ICBBE.2007.19
