Title :
Karhunen-Loeve-transformation of functional optical imaging of brain activity-consequences and implications
Author :
Hess, A. ; Scheich, H.
Author_Institution :
Fed. Inst. for Neurobiology, Magdeburg, Germany
Abstract :
Using the Karhunen-Loeve-transformation on sequential images of functional brain activity obtained by optical recording of intrinsic signals we were able to separate different components within the dynamic oximetric response, which are: (1) separate functional representations and vessel artifacts, (2) one component for more consistent local activation could be identified, (3) a second region of more spread activity could be differentiated
Keywords :
biomedical imaging; blood; brain; haemodynamics; image segmentation; image sequences; medical image processing; neurophysiology; oxygen; transforms; Karhunen-Loeve-transformation; brain activity; deoxyhemoglobin; dynamic oximetric response; functional optical imaging; gerbils; hemodynamic response; intrinsic signals; light reflection; local activation; more spread activity; one component; optical properties; optical recording; oxygenation status; oxyhemoglobin; second region; separate functional representations; sequential images; vessel artifacts; Animals; Brain; Hemodynamics; Histograms; Humans; Neuroimaging; Optical imaging; Optical recording; Optical reflection; Spatial resolution;
Conference_Titel :
Image Processing, 1996. Proceedings., International Conference on
Conference_Location :
Lausanne
Print_ISBN :
0-7803-3259-8
DOI :
10.1109/ICIP.1996.560769
