Karhunen-Loeve-transformation of functional optical imaging of brain activity-consequences and implications

Author

Hess, A. ; Scheich, H.

Author_Institution

Fed. Inst. for Neurobiology, Magdeburg, Germany

Volume

1

fYear

1996

fDate

16-19 Sep 1996

Firstpage

265

Abstract

Using the Karhunen-Loeve-transformation on sequential images of functional brain activity obtained by optical recording of intrinsic signals we were able to separate different components within the dynamic oximetric response, which are: (1) separate functional representations and vessel artifacts, (2) one component for more consistent local activation could be identified, (3) a second region of more spread activity could be differentiated

Keywords

biomedical imaging; blood; brain; haemodynamics; image segmentation; image sequences; medical image processing; neurophysiology; oxygen; transforms; Karhunen-Loeve-transformation; brain activity; deoxyhemoglobin; dynamic oximetric response; functional optical imaging; gerbils; hemodynamic response; intrinsic signals; light reflection; local activation; more spread activity; one component; optical properties; optical recording; oxygenation status; oxyhemoglobin; second region; separate functional representations; sequential images; vessel artifacts; Animals; Brain; Hemodynamics; Histograms; Humans; Neuroimaging; Optical imaging; Optical recording; Optical reflection; Spatial resolution;

fLanguage

English

Publisher

ieee

Conference_Titel

Image Processing, 1996. Proceedings., International Conference on

Conference_Location

Lausanne

Print_ISBN

0-7803-3259-8

Type

conf

DOI

10.1109/ICIP.1996.560769

Filename

560769