Surface Plasmon Resonance Biosensors and its Application

Over the last decade, the surface plasmon resonance (SPR) biosensor technique has received a great research interest. The major advantages of these sensors are its fast response and being able to detect the multi-analytes at one time. And its application areas include the detection of the biological analytes and the analysis of the biomolecular interactions where SPR biosensors provide with the benefits of the label-free real-time analytical technology. The general principles of SPR sensor action and the major SPR formats are briefly described in this paper, and the different commercialization of surface plasmon resonance sensor technology is presented, then the recent advances in the development and the applications of SPR biosensors are discussed. Finally the future prospects of SPR sensor technology are prospected.