Title :
Comprehensive Computational Analysis Approach for Alzheimer´s Disease
Author :
Shao, Jiaofang ; Tu, Qichao ; Chen, Ming
Author_Institution :
Coll. of Life Sci., Zhejiang Univ., Hangzhou
Abstract :
Alzheimer´s disease (AD) is characterized by Abeta plaques, amyloid angiopathy, and NFTs. The ongoing challenge is to integrate present resources as to discover the unkown mechanism and propose possible treatment targets. In this paper, we attempt to find the cause and treatment of AD with computational approach by making use of KEGG,GeneCards, Brenda, DrugBank and STRING.
Keywords :
biochemistry; brain; diseases; drugs; genetics; medical computing; molecular biophysics; neurophysiology; proteins; Abeta plaques; Alzheimer´s disease; Brenda; DrugBank; GeneCards; KEGG; STRING; amyloid angiopathy; computational analysis; Alzheimer´s disease; Biochemistry; Databases; Degradation; Drugs; Information retrieval; Inhibitors; Medical treatment; Peptides; Proteins;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
DOI :
10.1109/ICBBE.2007.278
