Title :
Simulation Study on Blood Glucose Control in Diabetics
Author :
Li, Chengwei ; Hu, Ruiqiang
Author_Institution :
Sch. of Electr. Eng. & Autom., Harbin Inst. of Technol., Harbin
Abstract :
In this paper, some theoretical analysis of the control of blood glucose levels in diabetic individuals is undertaken using a simple mathematical model of the dynamics of glucose and insulin interaction in the blood system developed by Bergman et al. One is an open-loop control, which is based on the mathematical model of insulin curve. The other is a closed-loop control, which is using a classic PID controller. The aim of the control performance was assessed in terms of its ability to track a setpoint (70 mg/dl)form initial state of hyperglycemia, as well as in response to a meal disturbance. The MATLAB simulation is performed to manifest the theoretical analysis. The development reported in this paper are expected to simplify the insulin delivery mechanism, thereby enhancing the quality of life of the patient.
Keywords :
blood; closed loop systems; diseases; mathematics computing; medical computing; medical control systems; open loop systems; patient treatment; sugar; three-term control; MATLAB simulation; PID controller; blood glucose control; closed-loop control; diabetics; glucose dynamics; hyperglycemia; insulin delivery mechanism; insulin interaction; mathematical model; open-loop control; Blood; Control system analysis; Diabetes; Insulation life; Insulin; MATLAB; Mathematical model; Open loop systems; Sugar; Three-term control;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
DOI :
10.1109/ICBBE.2007.285
