Title :
Controlled-Release of Materials in Calcium Alginate Microbeads Prepared by Microfluidic Device
Author :
Liu, Jing ; Liu, Kan ; Zhao, Li-Bo ; Zeng, Qian ; Guo, Zhi-Xiao ; Zhao, Xing-Zhong
Author_Institution :
Dept. of Phys., Wuhan Univ., Wuhan
Abstract :
Microencapsulation provides a simple and effective way to enclose bioactive material like drugs and cells, within a semi-permeable polymeric membrane, which could help the materials inside keep bioactive and release the polymeric substances or their products in a controlled fashion. The morphology of the microbeads was examined. The efficiency of these polymer microcapsules as containers for controlled release of loaded molecules was evaluated by encapsulating the microbeads with RBITC and investigating the release performance using an inverted optical fluorescent microscope.
Keywords :
bioMEMS; biomedical materials; drugs; encapsulation; microfluidics; polymers; bioactive material; calcium alginate microbeads; cells; drugs; inverted optical fluorescent microscope; microcapsules; microencapsulation; microfluidic device; polymer; semi-permeable polymeric membrane; Biological materials; Biomembranes; Calcium; Containers; Drugs; Microfluidics; Morphology; Optical control; Optical microscopy; Optical polymers;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2007. ICBBE 2007. The 1st International Conference on
Conference_Location :
Wuhan
Print_ISBN :
1-4244-1120-3
DOI :
10.1109/ICBBE.2007.320