DocumentCode
3056889
Title
Photomechanical targeted drug and gene delivery to central nervous systems
Author
Sato, Seiki ; Ando, Takehiro ; Satoh, Y. ; Nawashiro, Hiroshi ; Obara, M.
Author_Institution
Div. of Biomed. Inf. Sci., Nat. Defense Med. Coll. Res. Inst., Tokorozawa, Japan
fYear
2013
fDate
June 30 2013-July 4 2013
Firstpage
1
Lastpage
2
Abstract
We demonstrated efficient gene delivery to brain and spinal cord in rodents by applying photomechanical waves. The method was applied to recover motor function of rats with spinal cord injury. Photomechanical waves can also open the blood brain barrier.
Keywords
blood; brain; drug delivery systems; gene therapy; injuries; neurophysiology; blood brain barrier; brain; central nervous systems; gene delivery; photomechanical targeted drug delivery; photomechanical waves; rat motor function; rodents; spinal cord injury; Drugs; Fluorescence; Laser applications; Plasmas; Proteins; Rats;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2013 Conference on
Conference_Location
Kyoto
Type
conf
DOI
10.1109/CLEOPR.2013.6600121
Filename
6600121
Link To Document