Tumor ablation at low frequencies for preferential tumor heating: Initial ex-vivo tissue studies

Purpose: Radiofrequency (RF) ablation is a common treatment modality for inoperable liver cancer. Several studies have demonstrated that significant differences exist between the electrical properties of tumor and normal tissue, especially at lower frequencies. In this study, we investigated in an ex vivo setting whether the use of lower frequencies during ablation results in preferential heating of tumor tissue.