Title :
Laser manipulation of intracellular molecular dynamics in hippocampal neurons
Author :
Hosokawa, C. ; Ueda, Yuzuru ; Takeda, Nobuo ; Kudoh, Suguru N. ; Taguchi, Tomoko
Author_Institution :
Health Res. Inst., Ikeda, Japan
fDate :
June 30 2013-July 4 2013
Abstract :
We demonstrated laser manipulation of intracellular molecular dynamics in neurons to realize artificial control toward modulating synaptic transmission in a neuronal network. The optical trapping and assembling dynamics of synaptic vesicles and neural cell adhesion molecules in neurons was revealed by fluorescence analysis.
Keywords :
adhesion; brain; cellular biophysics; laser applications in medicine; molecular biophysics; neurophysiology; radiation pressure; artificial control; assembling dynamics; fluorescence analysis; hippocampal neurons; intracellular molecular dynamics; laser manipulation; neural cell adhesion molecules; neuronal network; optical trapping; synaptic transmission; synaptic vesicles; Biological neural networks; Charge carrier processes; Fluorescence; Neurons; Optical device fabrication; Optical imaging; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2013 Conference on
Conference_Location :
Kyoto
DOI :
10.1109/CLEOPR.2013.6600270
