Title :
Real-time detection of protein kinase a activity by a Si-based ARROW-B SPR biosensor
Author :
Hsin-Feng Hsu ; Zheng-Wen Lin ; Yang-Tung Huang ; Chiun-Jye Yuan
Author_Institution :
Dept. of Electron. Eng., Nat. Chiao Tung Univ., Hsinchu, Taiwan
fDate :
June 30 2013-July 4 2013
Abstract :
The ARROW-B SPR biosensor was proposed to provide label-free and high sensitivity characteristics to detect biomolecular interaction. In this work, Si-based ARROW-B SPR biosensors were designed and fabricated to detect protein kinase A activity.
Keywords :
biosensors; elemental semiconductors; enzymes; molecular biophysics; optical sensors; optical waveguides; silicon; surface plasmon resonance; Si; Si-based ARROW-B SPR biosensor; antiresonant reflecting optical waveguide-of-type B; biomolecular interaction; protein kinase A activity; real-time detection; surface plasmon resonance; Biosensors; Gold; Optical surface waves; Optical waveguides; Peptides; Power generation; Proteins;
Conference_Titel :
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2013 Conference on
Conference_Location :
Kyoto
DOI :
10.1109/CLEOPR.2013.6600625
