Title :
Optical measurement on membrane roughness of neuroblastoma cells treated with amyloid-beta peptide and electric fields
Author :
Huei-Jyuan Pan ; Ruei-Lin Wang ; Jian-Long Xiao ; Yu-Jen Chang ; Ji-Yen Cheng ; Yun-Ru Chen ; Chau-Hwang Lee
Author_Institution :
Res. Center for Appl. Sci., Acad. Sinica, Taipei, Taiwan
fDate :
June 30 2013-July 4 2013
Abstract :
We measured the membrane roughness of neuroblastoma cells by non-interferometric wide-field optical profilometry. We found that the peptide related to Alzheimer´s disease, Amyloid-beta 42, reduces membrane roughness, but direct-current electrical fields recover this effect.
Keywords :
biomedical optical imaging; biomembranes; cellular biophysics; diseases; light interferometry; neurophysiology; Alzheimer disease; amyloid-beta peptide; direct-current electrical fields; electric fields; membrane roughness; neuroblastoma cells; noninterferometric wide-field optical profilometry; optical measurement; Alzheimer´s disease; Biomedical optical imaging; Biomembranes; Cells (biology); Electric fields; Optical variables measurement; Peptides;
Conference_Titel :
Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2013 Conference on
Conference_Location :
Kyoto
DOI :
10.1109/CLEOPR.2013.6600629
