Title :
Multi-angle LUCAS for high-throughput on-chip cytometry
Author :
Su, Ting-Wei ; Seo, Sungkyu ; Erlinger, Anthony ; Ozcan, Aydogan
Author_Institution :
Electrical Engineering Department, University of California, Los Angeles, 90095, USA
Abstract :
We illustrate that by recording under-sampled diffraction patterns of cells at different illumination angles, we can achieve high-throughput on-chip characterization of a heterogeneous cell solution over an ultra large volume of ∼5 ml. This platform, termed multi-angle LUCAS, is especially promising for cost-effective point-of-care cell counting applications.
Keywords :
Biosensors; Fungi; Lenses; Lighting; Monitoring; Optical arrays; Optical imaging; Optical microscopy; Optical sensors; Sensor arrays; Biomedical Engineering; Cell Count; Equipment Design; Humans; Image Cytometry; Point-of-Care Systems; Schizosaccharomyces;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4649543