Title :
Automatic chromosome pairing using mutual information
Author :
Khmelinskii, Artem ; Ventura, Rodrigo ; Sanches, Joaão
Author_Institution :
Institute for Systems and Robotics / Instituto Superior Técnico, 1049-001 Lisbon, Portugal
Abstract :
Cytogenetics is a key tool in the detection of acquired chromosomal abnormalities and in the diagnosis of genetic diseases such as leukemia. The karyotyping is a set of procedures, in the scope of the cytogenetics, that produces a visual representation of the 46 chromosomes (called karyogram), paired and arranged in decreasing order of size.
Keywords :
Biological cells; Bones; Cells (biology); Diseases; Genetics; Manuals; Mutual information; Nonlinear optics; Optical microscopy; Testing; Algorithms; Biomedical Engineering; Chromosome Pairing; Chromosomes, Human; Female; Humans; Image Interpretation, Computer-Assisted; Karyotyping; Male; Software;
Conference_Titel :
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location :
Vancouver, BC
Print_ISBN :
978-1-4244-1814-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2008.4649562