Climbing fiber Purkinje cells twins: a search of extra-rare events in neural systems

The analysis of mechanisms of neural systems functions needs modern methodological tools. In particular, extremely specific knowledge is necessary for providing hypotheses on neural mechanisms with firm confirmations or persuasive rejections. It is well-known, that for the same type of problems, high-energy physics (HEP) is looking for an analysis of very rare, but informationally important events. We are presenting here attempts of experimental approach to understanding cerebellar functions, some features of which are alike the HEP search for rare events. The problem is following. Dunin-Barkowski proposed (1985) that study or relations between simple spike activity of cerebellar Purkinje cells (PC), controlled with the same climbing fiber (CF), can significantly help in understanding mechanisms of effective synaptic connection establishment in the cerebellum. The probability to pick up two or more PCs, controlled with the same CF is less than 10^-5. Here we analyse the problem and describe an attempt of search for described PC pairs