A nonenzymatic biosensor based on copper nanoparticles modified electrode for detection of acetylcholine

Author

Jabbari, Ali ; Heli, Hossein ; Hajjizadeh, Maryam ; Moosavi-Movahedi, Ali A.

Author_Institution

Department of Chemistry, Faculty of Science, K. N. Toosi University of Technology, P. O. Box: 16315-1618, Tehran, Iran

fYear

2008

fDate

20-25 Aug. 2008

Firstpage

2314

Lastpage

2317

Abstract

The electrocatalytic oxidation of acetylcholine (Ach) on copper microparticles modified carbon paste electrode (m-CPE) and copper nanoparticles-modified carbon paste electrode (n-CPE) was investigated. In the voltammogram recorded using m-CPE, a single anodic peak related to the oxidation of ACh was observed. Using n-CPE, however, two overlapped anodic peaks were observed. The amino acids oxidized on n-CPE at higher rates at lower potentials compared to m-CPE. A nonenzymatic amperometric biosensor was constructed and a simple analysis procedure was developed for the determination of ACh.

Keywords

Biosensors; Chemical technology; Copper; Electrodes; Nanobioscience; Nanoparticles; Oxidation; Scanning electron microscopy; Surface morphology; Transmission electron microscopy; Acetylcholine; Biosensing Techniques; Carbon; Copper; Electrodes; Metal Nanoparticles;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE

Conference_Location

Vancouver, BC

ISSN

1557-170X

Print_ISBN

978-1-4244-1814-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2008.4649661

Filename

4649661