• DocumentCode
    3071594
  • Title

    Fixed threshold modeling of an adjustable threshold integrate-and-fire neuronal model

  • Author

    Seydnejad, Saeid

  • Author_Institution
    Ottawa Heart Institute, University of Ottawa, Canada
  • fYear
    2008
  • fDate
    20-25 Aug. 2008
  • Firstpage
    2481
  • Lastpage
    2484
  • Abstract
    An action potential is generated when the membrane potential of a spiking neuron reaches a certain threshold. Although it is well-known that the threshold level of a neuron is not a fixed value and changes with time and neuronal parameters, its variation is often ignored in neuronal modeling due to the complexity of the analysis. Assuming a fixed threshold level, however, may produce non-realistic results. If we find a model to incorporate the impact of the variation of the threshold in a fixed threshold model we can benefit from the simplicity of the existing fixed-threshold models yet obtain more realistic results. It is shown here that, with some approximations, we can create a fixed threshold model for an integrate-and-fire neuronal model from an adjustable threshold model by some simple operations. Both models generate the same spike (action potential) pattern.
  • Keywords
    Biological neural networks; Biological system modeling; Biomembranes; Equations; Fires; Heart; Mathematical model; Neurons; Threshold voltage; Action Potentials; Differential Threshold; Electric Conductivity; Electric Stimulation; Humans; Membrane Potentials; Models, Biological; Models, Neurological; Models, Statistical; Neurons; Presynaptic Terminals; Reproducibility of Results; Synaptic Transmission; Time Factors;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
  • Conference_Location
    Vancouver, BC
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-1814-5
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/IEMBS.2008.4649703
  • Filename
    4649703