DocumentCode
3071594
Title
Fixed threshold modeling of an adjustable threshold integrate-and-fire neuronal model
Author
Seydnejad, Saeid
Author_Institution
Ottawa Heart Institute, University of Ottawa, Canada
fYear
2008
fDate
20-25 Aug. 2008
Firstpage
2481
Lastpage
2484
Abstract
An action potential is generated when the membrane potential of a spiking neuron reaches a certain threshold. Although it is well-known that the threshold level of a neuron is not a fixed value and changes with time and neuronal parameters, its variation is often ignored in neuronal modeling due to the complexity of the analysis. Assuming a fixed threshold level, however, may produce non-realistic results. If we find a model to incorporate the impact of the variation of the threshold in a fixed threshold model we can benefit from the simplicity of the existing fixed-threshold models yet obtain more realistic results. It is shown here that, with some approximations, we can create a fixed threshold model for an integrate-and-fire neuronal model from an adjustable threshold model by some simple operations. Both models generate the same spike (action potential) pattern.
Keywords
Biological neural networks; Biological system modeling; Biomembranes; Equations; Fires; Heart; Mathematical model; Neurons; Threshold voltage; Action Potentials; Differential Threshold; Electric Conductivity; Electric Stimulation; Humans; Membrane Potentials; Models, Biological; Models, Neurological; Models, Statistical; Neurons; Presynaptic Terminals; Reproducibility of Results; Synaptic Transmission; Time Factors;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE
Conference_Location
Vancouver, BC
ISSN
1557-170X
Print_ISBN
978-1-4244-1814-5
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/IEMBS.2008.4649703
Filename
4649703
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