Title :
Platelet response to cardiopulmonary bypass studied by gamma scintigraphy and platelet aggregometry
Author :
Li, J. ; Eberhart, R.C. ; Harris, F.B. ; Smith, B.P. ; Rajasubramanian, S. ; Pandit, A. ; Jessen, M.E. ; Chao, R. ; Constantinescu, A.
Author_Institution :
Southwestern Med. Center, Texas Univ., Dallas, TX, USA
Abstract :
Platelet response to surface modified (SMA) Cobe Duo membrane oxygenators was evaluated in a pig model of cardiopulmonary bypass (CPB) by gamma scintigraphic imaging and platelet impedance aggregometry (PIA). Comparisons of platelet deposition, blood pool platelet counts and platelet aggregation were made between SMA coated CPB circuits and uncoated circuits. The SMA-coated oxygenators exhibited decreases in foreign surface induced platelet aggregation and platelet deposition
Keywords :
blood; cardiology; electric impedance imaging; haemodynamics; lung; patient treatment; radioisotope imaging; SMA coated CPB circuits; SMA-coated oxygenators; blood pool platelet counts; cardiopulmonary bypass; foreign surface induced platelet aggregation; gamma scintigraphic imaging; gamma scintigraphy; pig model; platelet aggregation; platelet aggregometry; platelet deposition; platelet impedance aggregometry; platelet response; surface modified Cobe Duo membrane oxygenators; uncoated circuits; Adhesives; Biomedical imaging; Biomedical measurements; Biomembranes; Blood; Cardiology; Circuits; Coatings; Impedance; Time measurement;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.575038
