Platelet response to cardiopulmonary bypass studied by gamma scintigraphy and platelet aggregometry

Author

Li, J. ; Eberhart, R.C. ; Harris, F.B. ; Smith, B.P. ; Rajasubramanian, S. ; Pandit, A. ; Jessen, M.E. ; Chao, R. ; Constantinescu, A.

Author_Institution

Southwestern Med. Center, Texas Univ., Dallas, TX, USA

Volume

1

fYear

1995

fDate

20-25 Sep 1995

Firstpage

137

Abstract

Platelet response to surface modified (SMA) Cobe Duo membrane oxygenators was evaluated in a pig model of cardiopulmonary bypass (CPB) by gamma scintigraphic imaging and platelet impedance aggregometry (PIA). Comparisons of platelet deposition, blood pool platelet counts and platelet aggregation were made between SMA coated CPB circuits and uncoated circuits. The SMA-coated oxygenators exhibited decreases in foreign surface induced platelet aggregation and platelet deposition

Keywords

blood; cardiology; electric impedance imaging; haemodynamics; lung; patient treatment; radioisotope imaging; SMA coated CPB circuits; SMA-coated oxygenators; blood pool platelet counts; cardiopulmonary bypass; foreign surface induced platelet aggregation; gamma scintigraphic imaging; gamma scintigraphy; pig model; platelet aggregation; platelet aggregometry; platelet deposition; platelet impedance aggregometry; platelet response; surface modified Cobe Duo membrane oxygenators; uncoated circuits; Adhesives; Biomedical imaging; Biomedical measurements; Biomembranes; Blood; Cardiology; Circuits; Coatings; Impedance; Time measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference

Conference_Location

Montreal, Que.

Print_ISBN

0-7803-2475-7

Type

conf

DOI

10.1109/IEMBS.1995.575038

Filename

575038