Development of flexible microelectrode arrays for recording cortical surface field potentials

Author

Myllymaa, Sami ; Myllymaa, Katja ; Korhonen, Hannu ; Gureviciene, Irina ; Djupsund, Kaj ; Tanila, Heikki ; Lappalainen, Reijo

Author_Institution

Department of Physics, University of Kuopio, Finland

fYear

2008

fDate

20-25 Aug. 2008

Firstpage

3200

Lastpage

3203

Abstract

The fabrication, characterization and application of an 8-channel flexible microelectrode array for recording cortical surface field potentials is described. Polyimide-based microelectrode arrays were fabricated by using photolithography and physical vapour deposition (PVD) methods. Polyimide was chosen as the substrate and insulation material due to its suitable mechanical properties and biocompatibility. Electrodes and transmission lines were formed by sputter-coating of platinum thin films. Microelectrode arrays were characterized and tested successfully in vitro by impedance spectroscopy and in vivo by somatosensory evoked potential (SEP) recordings in rats. These tests indicated good performance and the potential of microelectrode arrays.

Keywords

Atherosclerosis; Biological materials; Chemical vapor deposition; Fabrication; Insulation; Lithography; Mechanical factors; Microelectrodes; Polyimides; Testing; Action Potentials; Algorithms; Animals; Cerebral Cortex; Electric Impedance; Electrodes; Electrophysiology; Evoked Potentials, Somatosensory; Materials Testing; Microelectrodes; Platinum; Rats; Spectrum Analysis; Stress, Mechanical; Titanium;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2008. EMBS 2008. 30th Annual International Conference of the IEEE

Conference_Location

Vancouver, BC

ISSN

1557-170X

Print_ISBN

978-1-4244-1814-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2008.4649884

Filename

4649884