Title :
DMUSIC algorithm for 2D NMR signals
Author :
Li, Ye ; Razavilar, J. ; Liu, K. J Ray
Author_Institution :
Dept. of Electr. Eng., Maryland Univ., College Park, MD, USA
Abstract :
The authors propose a super-resolution scheme for the parameter estimation of two-dimensional (2-D) NMR signals. 2-D NMR signals can be modeled as the summation of 2-D damped sinusoids. The frequencies and the damping factors of 2-D damped sinusoids play important roles in protein structure determination using 2-D NMR spectroscopy. The authors develop a super-resolution frequency and damping factor estimation algorithm-the damped MUSIC (DMUSIC) algorithm. Since the DMUSIC algorithm makes full use of the rank-deficiency and the Hankel property of the data matrix composed of the 2-D NMR data, compared with other NMR data analysis algorithms, it can resolve NMR spectroscopy signals under a low signal to noise ratio. The performance of the DMUSIC algorithm is demonstrated by simulations
Keywords :
NMR spectroscopy; biological NMR; medical signal processing; molecular biophysics; parameter estimation; proteins; spectral analysis; 2-D damped sinusoids summation; 2D NMR signals; DMUSIC algorithm; Hankel property; damping factor estimation; data matrix; protein structure determination; rank-deficiency; signal to noise ratio; super-resolution scheme; Damping; Data analysis; Frequency estimation; Multiple signal classification; Nuclear magnetic resonance; Parameter estimation; Proteins; Signal resolution; Spectroscopy; Two dimensional displays;
Conference_Titel :
Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference
Conference_Location :
Montreal, Que.
Print_ISBN :
0-7803-2475-7
DOI :
10.1109/IEMBS.1995.575208